Super CitriMax is a unique, patented extract of Garcinia cambogia, a fruit, standardized to 60% (-)-hydroxycitric acid (HCA) bound to calcium and potassium. The unique double-salt configuration of Super CitriMax makes HCA highly soluble, bioavailable and efficacious. HCA is an established inhibitor of the ATP citrate, known to catalyze the conversion of citrate into acetyl coenzyme A, a primary building block for fatty acid synthesis. Due to its unique biochemistry, Super CitriMax not only inhibits the synthesis of fat but works through distinctive mechanisms of action that account for its superior bioefficacy for weight control. Super CitriMax has been clinically proven to suppress appetite by enhancing serotonin availability, leading to increased satiety with a reduction in caloric intake as well as balanced energy metabolism. Super CitriMax has also been shown to increase fat burning.
(-)-Hydroxycitric acid (HCA), a popular dietary supplement for weight loss, is an organic acid similar to citric acid found in citrus fruits such as oranges and lemons, but with remarkably different properties: HCA has been shown to reduce appetite, inhibit fat synthesis and decrease body weight without stimulating the central nervous system. HCA occurs predominantly in the fruit rind of Garcinia cambogia, a tree native to South and Southeast Asia.
HCA has been sold as a dietary supplement since 1994, but the research on HCA stretches back over 30 years. In 1969, researchers at Brandeis University demonstrated the role of HCA as an inhibitor of the Krebs/citric acid cycle.8 They showed that HCA is a competitive inhibitor of ATP-citrate lyase. Inhibiting ATP-citrate lyase diverts carbohydrates away from fat synthesis and towards the synthesis of stored energy in the form of glycogen. Increased glycogen levels are believed to send a signal to the brain that the body is full, resulting in reduced appetite and food intake.
HCA may also be able to stimulate serotonin release and inhibit its reuptake in the body. Serotonin (5-HT), a neurotransmitter, is involved in a wide range of behavioral functions in the body, including mood and appetite control. Studies show that serotonin affects eating behavior and body weight. Increased plasma levels are associated with decreased food intake, reduced weight gain and increased energy expenditure.
A randomized placebo-controlled study was conducted involving overweight adults demonstrated that 500 mg HCA (as CitriMax®) taken three times per day before meals for eight weeks resulted in 215% greater weight loss than those taking a placebo, without side effects associated with diet stimulants. Furthermore, a significant reduction was also observed in cholesterol and triglyceride levels.
Super CitriMax is not a central nervous system stimulant and does not cause nervousness, rapid heart rate, high blood pressure or insomnia like some other diet supplements.